復(fù)旦征集曹氏染色體辨別“曹操墓”真?zhèn)?/title> <meta name="filetype" content="0"> <meta name="publishedtype" content="1"> <meta name="pagetype" content="1"> <meta name="catalogs" content="39"> <meta name="contentid" content="1237028"> <meta name="publishdate" content="2010-01-27"> <meta name="author" content="張曉靜"> <meta name="source" content="新華網(wǎng)"> <meta name="keywords" content="曹操"> <meta name="description" content="社會(huì),中國臺(tái)灣,臺(tái)獨(dú),國民黨,民進(jìn)黨,臺(tái)商,臺(tái)胞,馬英九,陳水扁,兩岸,統(tǒng)一,謝長廷,公投,臺(tái)臺(tái)灣,入聯(lián),三通,大陸,臺(tái)辦,立委,立法院" /> <meta content="社會(huì),中國臺(tái)灣,臺(tái)獨(dú),國民黨,民進(jìn)黨,臺(tái)商,臺(tái)胞,馬英九,陳水扁,兩岸,統(tǒng)一,謝長廷,公投,臺(tái)臺(tái)灣,入聯(lián),三通,大陸,臺(tái)辦,立委,立法院" name="keywords" /> <link rel="stylesheet" type="text/css" href="../../../../images/newsletter_view.css"> <style>  </style> <script type="text/javascript" src="../../../../images/txtsize.js"></script> <script type="text/javascript" src="../../../../images/jquery.js"></script> <script 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class="mainbox_01"style="text-align:center;color:#006aa2"> 時(shí)間：2010-01-27 08:50　　　來源：新華網(wǎng)</div> <div id="h1hhhffj1h" class="mainbox_02" id="textsize"><P>　　新華網(wǎng)上海1月26日專電（俞菀、潘旭）為辨別河南東漢高陵是否是曹操墓，復(fù)旦大學(xué)現(xiàn)代人類學(xué)教育部重點(diǎn)實(shí)驗(yàn)室26日宣布，決定向全國征集曹氏后代的男性染色體，通過對(duì)他們Y染色體的歸類總結(jié)，確認(rèn)出土骸骨是否屬于曹操家族。 </P> <P>　　根據(jù)史學(xué)研究，曹操可能是夏侯氏的子代。由于現(xiàn)在距當(dāng)時(shí)一千多年，考慮到遷移等復(fù)雜情況，現(xiàn)在的曹姓或夏侯姓不一定就是曹操的家族或支族，因此除了召集可以提供家譜的曹氏后人外，實(shí)驗(yàn)室還召集其他曹姓男子，擴(kuò)大樣本數(shù)量，歸納出多種類型的曹姓或夏侯姓的Y染色體類型，再與出土骸骨的Y染色體進(jìn)行比對(duì)，看能否與其中之一匹配。 </P> <P>　　所謂Y染色體類型，主要是依照Y染色體上的堿基對(duì)突變來歸納分類。專家介紹，在人類基因組上，每傳代17次堿基對(duì)會(huì)產(chǎn)生一次突變，稱為SNP突變，即單核苷酸多態(tài)。氏族的男性成員的Y染色體中都會(huì)有特定的SNP突變信息，后代會(huì)將其遺傳下去。因此，從SNP突變信息上看，每個(gè)家族都會(huì)有各自的Y染色體類型。 </P> <P>　　項(xiàng)目負(fù)責(zé)人李輝告訴記者，曹操Y染色體的SNP突變信息幾乎百分之百能在他的后代Y染色體上找到，后代丟失的概率只有10的18次方分之一。 </P> <P>　　李輝表示，目前實(shí)驗(yàn)室基因檢測數(shù)據(jù)庫中已保存有48位曹姓男性的Y染色體，可以分為3類，希望可以搜集數(shù)百個(gè)甚至更多的曹姓和夏侯姓的樣本數(shù)量，就可囊括更多曹姓或夏侯姓的Y染色體的類型，為比對(duì)骸骨提供更扎實(shí)的依據(jù)。 </P> <P>　　“比對(duì)成功后至少可以證明陵墓主人屬于曹氏和夏侯氏家族。”李輝說。 </P> <P>　　中國魏晉南北朝史學(xué)會(huì)理事、復(fù)旦大學(xué)歷史系教授韓晟說，如果這項(xiàng)技術(shù)能夠證明墓穴主人屬于曹操家族的話，再根據(jù)考古學(xué)和歷史學(xué)家們對(duì)墓穴出土文物的相關(guān)研究成果，確定墓主人是曹操就不困難了。 </P> <P>　　針對(duì)出土骸骨的DNA檢測問題，李輝表示，檢測全基因組當(dāng)然受物理?xiàng)l件的限制，但是根據(jù)曹操Y染色體SNP突變特征去尋找骸骨上的某個(gè)堿基對(duì)還是完全有可行性的。 </P> <P>　　據(jù)介紹，在上世紀(jì)90年代國際學(xué)術(shù)界就已將Y染色體分析運(yùn)用在人類學(xué)研究中，復(fù)旦專家組的《亞洲人群遺傳多樣性圖譜》《遺傳證據(jù)支持漢文化傳播的人口擴(kuò)張模式》等相關(guān)研究也曾分別發(fā)表在美國的《科學(xué)》雜志和《自然》雜志上。</P> <P style="MARGIN: 0px" align=center target="_blank"><A href="http://jssljx.com/xwzx/" target=_blank><STRONG><FONT color=#0000ff>點(diǎn)擊更多新聞進(jìn)入新聞中心</FONT></STRONG></A><FONT color=#0000ff>　</FONT><A href="http://jssljx.com/xwzx/dl/shh/" target=_blank><STRONG><FONT color=#0000ff>社會(huì)新聞</FONT></STRONG></A><STRONG><FONT 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